UK architecture firm Foster + Partners, together with Berkley's ELS, has been chosen to design the $121m renovation of 50 UN Plaza in San Francisco.
A historic federal building in the Civic Centre area, the six-storey, 32,000m² Beaux-Arts building has been vacant since 2007.
The US General Services Administration (GSA), to which the building belongs, said the renovation will bring the building back to life as an attractive office space.
Apart from architectural design, the project will also cover a seismic upgrade with new electrical, heating and plumbing systems.
The UN Plaza was designed in 1936 by Arthur Brown Jr.
The GSA received $5.55bn as part of the $130bn federal stimulus fund for building renovation and construction, under the Recovery Act.